Remarkable precision, perfection and logic of biomolecules and biochemical pathways achieved during evolution underlie all aspects of surrounding life and human activities. Likewise, scientific progress in biochemistry is immense and is a driving force of medicine, biotechnology, agriculture, and food industry among other areas. Irrespective of what path of career you will chose in future, biochemical knowledge will always help and sometimes will be even critically necessary in problem-solving.
Instead of providing you with all-embracing theoretical knowledge of biochemistry, which would take many years of studies, the course shall rather make you interested in the subject
and help navigate you in finding explanations for various biological phenomena. Furthermore, the course will facilitate your better understanding of cell biology, immunology and genetics, i.e. other subjects closely related to biochemistry.
KE0073 Biochemistry, continuation, 7.5 CreditsBiokemi, fortsättningskurs
Education cycleBachelor’s level
Advanced study in the main fieldFirst cycle, less than 60 credits from first-cycle courses as entry requirements(G1F)
Prior knowledgeKnowledge and skills in fundamentals of chemistry corresponding to 15 hp
ObjectivesThe aim of the course is to give advanced knowledge and skills within biochemistry.
On completion of the course, the student should be able to:
1. account at a general level for different technologies for analysis and structural studies of proteins
2. describe and illustrate principles of enzyme catalysis, kinetics and regulation
3. identify structural and functional parts in protein molecules and relate them to the biological function of the protein (e g catalytic mechanism at enzymes, receptor mechanism)
4. account at a general level for methods to generate and use biological information (gene technology and bioinformatics)
5. describe how lipids carbohydrates and proteins are metabolized and synthesised
6. present and discuss metabolism in connection with overweight nutritional intake, training, starvation, diabetes and cancer
7. relate symptoms on deficit/surplus/genetic defects to metabolic disturbances at a biochemical level
8. present biochemical problem-solving in the form of seminars
9. carry out processing and analysis of data from biochemical experiments and to present these in writing
ContentLectures, teaching sessions, computer practicals, seminars and exercises are used in the course. Some activities are conducted in small groups, while others are not.
Roll call and course introduction, seminars, computer practicals, and group exercises are compulsory components.
Written and oral presentations are carried out through presenting results from computer practicals , seminars and group exercises. The course consists of both biochemical theory and of solving biochemical problem.
The following items are treated in lectures, teaching sessions, seminars and laboratory sessions:
- technologies for purification, analysis and structural studies of proteins
- gene technology, bioinformatics, "omics" (genomics, transcriptomics, proteomics, metabolomics), recombinant gene expression
- enzymes: catalytic mechanisms, regulation of activity, allostery, efficiency, specificity, enzyme-assays
- carbohydrate metabolism: the pentose phosphate pathway, gluconeogenesis, the glycogen, reciprocal regulation
- metabolism of fats, lipids, amino acids, proteins, nucleotides, nitrogen metabolism
- integration of metabolism: nutritional intake, homeostasis, hormonal control, body weight, BMI, overweight, training, starvation, alcohol
-membrane channels, pumps, signal transduction, sensory systems, receptors
Formats and requirements for examinationExamination formats: Written examination and approved compulsory activities .
Passing the course requires: Approved examination, approved participation in compulsory activities.
- If the student fails a test, the examiner may give the student a supplementary assignment, provided this is possible and there is reason to do so.
- If the student has been granted special educational support because of a disability, the examiner has the right to offer the student an adapted test, or provide an alternative assessment.
- If changes are made to this course syllabus, or if the course is closed, SLU shall decide on transitional rules for examination of students admitted under this syllabus but who have not yet passed the course.
- For the examination of a degree project (independent project), the examiner may also allow the student to add supplemental information after the deadline. For more information on this, please refer to the regulations for education at Bachelor's and Master's level.
- The right to take part in teaching and/or supervision only applies to the course date to which the student has been admitted and registered on.
- If there are special reasons, the student may take part in course components that require compulsory attendance at a later date. For more information on this, please refer to the regulations for education at Bachelor's and Master's level.
Additional informationThe entry requirements can be achieved e g by having followed the courses in basic chemistry I and II comprising in total 22.5 credits with at least 15 credits passed results.
Some learning activities may be conducted in English.