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KE0065

Analytical Natural Products Chemistry

The course is intended to give the student knowledge about the most important natural products. Occurrence, chemical properties and analytical methods will be covered.
The following natural products will be covered: Carbohydrates, lipids, nucleic acids, amino acids, peptides, terpenes, steroids and alkaloids.
The following analytical techniques will be covered: Spectroscopy (NMR, MS, IR, UV), chromatography (GC, HPLC, TLC).

The course evaluation is now closed

KE0065-30257 - Course evaluation report

Once the evaluation is closed, the course coordinator and student representative have 1 month to draft their comments. The comments will be published in the evaluation report.

Additional course evaluations for KE0065

Academic year 2019/2020

Analytical Natural Products Chemistry (KE0065-30057) 2020-02-20 - 2020-03-24

Academic year 2018/2019

Analytical Natural Products Chemistry (KE0065-30115) 2019-02-21 - 2019-03-25

Academic year 2017/2018

Analytical Natural Products Chemistry (KE0065-30007) 2018-02-15 - 2018-03-20

KE0065 Analytical Natural Products Chemistry, 7.5 Credits

Analytisk naturproduktkemi

Syllabus approved

2016-12-02

Subjects

Chemistry Food science

Education cycle

Bachelor’s level

Advanced study in the main field

First cycle, less than 60 credits from first-cycle courses as entry requirements(G1F)

Grading scale

5:Pass with Distinction, 4:Pass with Credit, 3:Pass, U:Fail The requirements for attaining different grades are described in the course assessment criteria which are contained in a supplement to the course syllabus. Current information on assessment criteria shall be made available at the start of the course.

Language

English

Prior knowledge

15 credits basic knowledge and skills in general, organic and biochemistry. At least 5 credits of the 15 must be in organic chemistry.
Exemption from entry requirements in Swedish.

Objectives

After completed course, the student will be able to:
- describe the names, structures, characteristic properties, occurrence, biosynthesis, as well as suitable methods for the analysis, for the majority of the most important groups of natural products.
- describe the principles for some of the more common methods for chemical analysis and separation.
- execute and interpret data from experiments based some of the more common methods for chemical analysis and separation.
- search and critically evaluate scientific information
- analyse, report and present chemical results both in written and in oral form.

Content

Lectures, seminars, exercise sessions and laboratory work are used during the course. Course introduction, laboratory introduction, laboratory work, execution of project work as well as presentation of the project, and seminar and exercise on retrieval of scientific information are compulsory activities.

Properties, such as names, structures and reactivities, occurrence and biosynthesis, of the following groups of natural products will be covered in the course:
- carbohydrates
- amino acids
- peptides/proteines
- nucleic acids
- fatty acids
- polyketides
- terpenes
- steroides
- phenylpropanoides
- alkaloides

In addition, the following techniques for isolation and analysis of natural products will be covered:
- extraction methods
- chromatography (GC, HPLC, TLC, etc.)
- spectroscopy (NMR, MS, UV/VIS, IR, etc.)

Each student will participate in a small project in which a natural compound will be isolated, purified, characterised and/or quantified.
One course part deals with retrieval of scientific information.

Formats and requirements for examination

Passed written final exam, passed oral and written reports of the project, passed compulsory laboratory reports and active participation in other compulsory activities
  • If the student fails a test, the examiner may give the student a supplementary assignment, provided this is possible and there is reason to do so.
  • If the student has been granted special educational support because of a disability, the examiner has the right to offer the student an adapted test, or provide an alternative assessment.
  • If changes are made to this course syllabus, or if the course is closed, SLU shall decide on transitional rules for examination of students admitted under this syllabus but who have not yet passed the course.
  • For the examination of a degree project (independent project), the examiner may also allow the student to add supplemental information after the deadline. For more information on this, please refer to the regulations for education at Bachelor's and Master's level.

Other information

  • The right to take part in teaching and/or supervision only applies to the course date to which the student has been admitted and registered on.
  • If there are special reasons, the student may take part in course components that require compulsory attendance at a later date. For more information on this, please refer to the regulations for education at Bachelor's and Master's level.

Additional information

The prerequisites can be fulfilled by having followed the courses KE0062, KE0063 and KE0064 and:
i. having passed course modules corresponding to at least 15 credits within the courses mentioned above
and
ii. having passed course modules corresponding to at least 5 credits in organic chemistry

The course is given in Swedish if only Swedishspeaking teachers and students participate.

Responsible department

Department of Molecular Sciences

Further information

Determined by: Programnämnden för utbildning inom naturresurser och jordbruk (PN - NJ)
Replaces: KE0055, KE0057
There are no Grading criteria posted for this course
1) Natural products: The Secondary Metabolites
Author: James R. Hansson
ISBN: 0-85404-490-6.
Comments: Suggested reading: -Analytical chemistry: p. 28-30 -Lipids and polyketides: p. 105-111 -Terpenes: p. 6-14, 112-119 -Phenylpropanoids: p. 15-17, 119-121 -Alkaloids: p. 18-21, 121-124
2) Chemistry. Human Activity, Chemical Reactivity
Author: P. Mahaffy, R. Tasker, B. Bucat, J.C. Kotz, G.C. Weaver, P.M. Treichel, J.E. McMurry
ISBN: 9780176684082
Comments: Suggested reading: -Analytical chemistry: p. 18, 67-81, 73-74, 306-317, 323, 345, 446, 785-787, 832-839, 878-880, 913-919, 990-993, 1046-1048 -Carbohydrates: Chapter: 29.1 & 29.2, & p. 961-962 -Peptides: Chapter 29.1 & 29.3 -Lipids and polyketides: Chapter 24.12 -Alkaloids: Chapter 25.
3) Compendium - Lectures
Comments: Provided electronically via Canvas.
4) Compendium - Laboratory exercises
Comments: Provided electronically via Canvas.
5) Compendium - Exercises and solutions
Comments: Provided electronically via Canvas.
6) Chemistry (3rd ed)
Author: Blackman, Bottle, Schmid, Mocerino and Wille
ISBN: 9780730311058 (paperback)
Comments: Suggested reading: -Analytical chemistry: p. 874-940. -Carbohydrates: p. 955-958, 984-1008 -Peptides: p. 1060-1090 -Lipids and polyketides: p. 1043-1047 -Terpenes: p. 942, p. 961 -Alkaloids: p. 848.

Course facts

The course is offered as an independent course: Yes The course is offered as a programme course: Agriculture Programme - Food Tuition fee: Tuition fee only for non-EU/EEA/Switzerland citizens: 19027 SEK Cycle: Bachelor’s level
Subject: Chemistry Food science
Course code: KE0065 Application code: SLU-30257 Location: Uppsala Distance course: No Language: English Responsible department: Department of Molecular Sciences Pace: 100%